Search results for "West Nile"
showing 9 items of 9 documents
Prediction of unfavorable outcomes in West Nile virus neuroinvasive infection - Result of a multinational ID-IRI study
2019
Background: WNV causes 1.4% of all central nervous system infections and is the most common cause of epidemic neuro-invasive disease in humans. Objectives: Our main objective was to investigate retrospectively West Nile virus neuroinvasive disease (WNND) cases hospitalized during 2010–2017 and identified factors that can influence prognosis. Study design: We documented the demographic, epidemiologic, clinical and laboratory data of WNND and identified factors that can influence prognosis. The data were recruited through Infectious Diseases International Research Initiative (ID-IRI), which serves as a network for clinical researches. Results: We investigated 165 patients with WNND in 10 coun…
Harnessing Big Data for Communicable Tropical and Sub-Tropical Disorders: Implications From a Systematic Review of the Literature
2018
aim: According to the World Health Organization (WHO), communicable tropical and sub-tropical diseases occur solely, or mainly in the tropics, thriving in hot, and humid conditions. Some of these disorders termed as neglected tropical diseases are par- ticularly overlooked. Communicable tropical/sub-tropical diseases represent a diverse group of communicable disorders occurring in 149 countries, favored by tropical and sub-tropical conditions, affecting more than one billion people and imposing a dramatic societal and economic burden. methods: A systematic review of the extant scholarly literature was carried out, searching in PubMed/MEDLINE and Scopus. The search string used included prope…
West Nile virus in Spain: Forecasting the geographical distribution of risky areas with an ecological niche modelling approach.
2021
West Nile virus (WNV), a well-known emerging vector-borne arbovirus with a zoonotic life cycle, represents a threat to both public and animal health. Transmitted by ornithophilic mosquitoes, its transmission is difficult to predict and even more difficult to prevent. The massive and unprecedented number of human cases and equid outbreaks in Spain during 2020 interpellates for new approaches. For the first time, we present an integrate analysis from a niche perspective to provide an insight to the situation of West Nile disease (WND) in Spain. Our modelling approach benefits from the combined use of global occurrence records of outbreaks of WND in equids and of its two alleged main vectors i…
West Nile Disease (WND) in Sicily
2012
WND is an emerging vector-borne zoonosis caused by an RNA virus included in the Japanese encephalitis group within the Flavivirus genus. In Italy, after the first appearance in Tuscany in 1998, West Nile Virus (WNV) has been continuously circulating since 2008. A National Surveillance Program consisting of monitoring horses, “sentinel poultries”, wild bird mortality and mosquitoes is active in the entire national territory since 2002. Authors describe the outbreaks which occurred in Sicily in 2010 and 2011. Case study: Between September-October 2010, seven horses from the western part of the island, in the Trapani province, showed neurological symptoms. In October 2011, another two horses s…
Importance of dogs as sentinels of West Nile Virus activity in urban and suburban areas
2012
Background: West Nile Virus (WNV) is a virus included in the Japanese encephalitis sero-complex within the genus Flavivirus. In August 2010, cases of West Nile disease were reported for the first time in Sicily. Neurological symptomswere observed in native horses resident in the rural areas around the province of Trapani, in the western part of the island. During the epidemic, important critical questions onwhen the viruswas introduced in the area and aboutwhether the virus had circulated/was circulating in theurban area, emerged and needed to be answered. A retrospective study using dog serum samples was designed to answer these questions. Methods: Between January 2009 and September 2010, …
Opsoclonus-myoclonus syndrome attributable to West Nile encephalitis: a case report
2014
Introduction Opsoclonus-myoclonus syndrome is a very rare neurological disorder associated with some viral infections and exceptionally with the West Nile virus. Case presentation A 57-year-old Caucasian woman presented with fever, dizziness, balance difficulties, vomiting, dancing eye, altered speech, tremor, generalized myoclonus and failure to rise or stand. Our objective is to describe a patient with West Nile infection, which was identified both in her serum and cerebrospinal fluid and was associated with encephalitis and opsoclonus-myoclonus-ataxia syndrome. Conclusions Opsoclonus-myoclonus-ataxia syndrome continued for 4 weeks after onset, when she died. There was no evidence for any…
Specific Recognition of the 5′-Untranslated Region of West Nile Virus Genome by Human Innate Immune System
2022
In the last few years, the sudden outbreak of COVID-19 caused by SARS-CoV-2 proved the crucial importance of understanding how emerging viruses work and proliferate, in order to avoid the repetition of such a dramatic sanitary situation with unprecedented social and economic costs. West Nile Virus is a mosquito-borne pathogen that can spread to humans and induce severe neurological problems. This RNA virus caused recent remarkable outbreaks, notably in Europe, highlighting the need to investigate the molecular mechanisms of its infection process in order to design and propose efficient antivirals. Here, we resort to all-atom Molecular Dynamics simulations to characterize the structure of th…
Neurological manifestations of the West Nile virus infection in some cases found in the clinic of infectious diseases in Sibiu, Romania
2014
Background The neurological manifestations in the West Nile virus infections are present in less than 1% of the diagnosed cases, neurological manifestations which may take many different forms, from encephalitis, meningitis, GuillainBarre syndrome, optic neuritis to polio-like manifestations. We aimed to evaluate the clinical and paraclinical aspects of the cases presenting neurological infections caused by the West Nile virus diagnosed and treated in our clinic.
Further spread of West Nile virus in Italy.
2010
Following two consecutive years of West Nile virus (WNV) circulation in Italy, new foci of infection were observed in August 2010 in Sicily and Molise in southern and central Italy, respectively. These incidents were far from the previous infected area in northern Italy, thereby confirming the ability of WNV to spread to new areas and affect new host populations. © Istituto G. Caporale 2010.